Relapsing Polychondritis: Difference between revisions

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== Clinically Relevant Anatomy<br>  ==
== Clinically Relevant Anatomy<br>  ==


Relapsing polychondritis (RP) is a rare multisystem autoimmune disease of unknown origin characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues.<br>  
Relapsing polychondritis (RP) is a rare multisystem autoimmune condition with an unknown cause. It is characterized by recurring episodes of inflammation that lead to the gradual destruction of various cartilaginous tissues in the body. This includes elastic cartilage found in the ears and nose, hyaline cartilage in peripheral joints, fibrocartilage in the spine, and cartilage in the tracheobronchial system. RP can affect structures rich in proteoglycans, such as those in the eye, heart, blood vessels, and inner ear.<ref>GERGELY P. Relapsing polychondritis. Best Practice & Research Clinical Rheumatology. 2004 Oct;18(5):723–38</ref>  


== Etiology ==
== Etiology ==

Revision as of 08:43, 2 September 2023

Clinically Relevant Anatomy
[edit | edit source]

Relapsing polychondritis (RP) is a rare multisystem autoimmune condition with an unknown cause. It is characterized by recurring episodes of inflammation that lead to the gradual destruction of various cartilaginous tissues in the body. This includes elastic cartilage found in the ears and nose, hyaline cartilage in peripheral joints, fibrocartilage in the spine, and cartilage in the tracheobronchial system. RP can affect structures rich in proteoglycans, such as those in the eye, heart, blood vessels, and inner ear.[1]

Etiology[edit | edit source]

The etiology of RP remains unknown so far. Studies have shown the association of both cellular immunity changes and abnormal autoantibody response in RP.

Clinical Presentation[edit | edit source]

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Diagnostic Procedures[edit | edit source]

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Outcome Measures[edit | edit source]

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Management / Interventions
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Differential Diagnosis
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Resources
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References[edit | edit source]

  1. GERGELY P. Relapsing polychondritis. Best Practice & Research Clinical Rheumatology. 2004 Oct;18(5):723–38