Myalgic Encephalomyelitis or Chronic Fatigue Syndrome: Difference between revisions
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== Differential Diagnosis == | == Differential Diagnosis == | ||
The following are possible differential diagnoses<ref name="Goodman">Goodman CC., Fuller KS. Pathology: implications for the physical therapist. 3rd ed. St. Louis: Saunders; 2009.</ref>: | |||
*Fibromyalgia | |||
*Patients usually demonstrate with increased pain, while patients with CFS experience greater fatigue. Some consider CFS and fibromyalgia to be one in the same; others believe CFS is an early form of fibromyalgia. | |||
*Mononucleosis | |||
*Lyme Disease | |||
*Thyroid conditions | |||
*Diabetes | |||
*MS | |||
*Various Cancers | |||
*Depression | |||
*Bipolar disorder | |||
*Myalgic encephalomyelitis<ref name="White">White PD, Goldsmith KA, Johnson AL, et al. Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomized trial. Lancet. 2011;377:823-836.</ref><br> | |||
== Case Reports/ Case Studies == | == Case Reports/ Case Studies == | ||
Revision as of 05:38, 1 April 2012
Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!
Original Editors - Sarah Carlisle & Jill Thompson from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Lead Editors - Your name will be added here if you are a lead editor on this page. Read more.
Definition/Description[edit | edit source]
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Prevalence[edit | edit source]
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Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
While studies have investigated the use of various medications, none have been found to have consistent results. However, the following drugs are used to address and manage symptoms[1]:
- Medications to reduce pain, discomfort, and fever
- Medications to treat anxiety
- Medications to treat sleep disturbance (amitryptyline, nefazodone[2])
- Medications to treat joint pain (amytryptyline[2])
- Medications to treat depression (sertralin, paroxetine, nefazodone[2])
- Anti-inflammatory drugs (aspirin, acetaminophen[2])
- NSAIDS to address headache relief[2]
- Deydroepiandrosterone (DHEA) was found in a pilot study to significantly reduce the pain, helplessness, anxiety, thinking, memory, and activities of daily living difficulties associated with CFS; however, further research is necessary[2].
- Based on current evidence corticosteroids cannot be recommended for CFS due to complications of long-term use, Mineralcorticoids and Intravenous Immunoglobulin are not recommended either and need further research[2][3]
Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
The following are possible differential diagnoses[4]:
- Fibromyalgia
- Patients usually demonstrate with increased pain, while patients with CFS experience greater fatigue. Some consider CFS and fibromyalgia to be one in the same; others believe CFS is an early form of fibromyalgia.
- Mononucleosis
- Lyme Disease
- Thyroid conditions
- Diabetes
- MS
- Various Cancers
- Depression
- Bipolar disorder
- Myalgic encephalomyelitis[5]
Case Reports/ Case Studies[edit | edit source]
add links to case studies here (case studies should be added on new pages using the case study template)
Resources
[edit | edit source]
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Recent Related Research (from Pubmed)[edit | edit source]
see tutorial on Adding PubMed Feed
Failed to load RSS feed from http://eutils.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss_guid=1NGmwZeh8JwVIzrKgHG1LrDm0izTr7ViJiDkSYAY2BW5hiXsx0|charset=UTF-8|short|max=10: Error parsing XML for RSS
References[edit | edit source]
see adding references tutorial.
- ↑ Teitel AD MD MBA, Zieve D MD MHA. Chronic fatigue syndrome. PubMed Health: A.D.A.M. Medical Encyclopedia. 2012. Available from: PubMed.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gur, A., Oktayoglu, P. Central nervous system abnormalities in fibromyalgia and chronic fatigue syndrome: new concepts in treatment. Current Pharmaceutical Design. 2008: 14;1274-1294. Available from: PubMed.
- ↑ Vinjamury, S.P. MD, Singh, B.S. PhD. Ayurvedic Treatment of chronic fatigue syndrome-a case report. Alternative Therapies in Health and Medicine. Sept/Oct 2005: 11(5);76-78. Available from: PubMed.
- ↑ Goodman CC., Fuller KS. Pathology: implications for the physical therapist. 3rd ed. St. Louis: Saunders; 2009.
- ↑ White PD, Goldsmith KA, Johnson AL, et al. Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomized trial. Lancet. 2011;377:823-836.
