Spinal cord anatomy: Difference between revisions

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== Introduction  ==
== Introduction  ==
The Nervous System is divided into two main divisions.<ref name="Barker">Barker; Barasi; Neal. Neuroscience at a glance; Blackwell science Ltd; 1999</ref>&nbsp;
The nervous system is divided into the central nervous system (brain and spinal cord considered upper motor neurons) and the peripheral nervous system (nerves that enter and exit the spinal cord considered lower motor neurons).<ref name="Barker">Barker; Barasi; Neal. Neuroscience at a glance; Blackwell science Ltd; 1999</ref> Information to and from the muscles, glands, organs and sensory receptors are carried through the peripheral nervous system, which is divided into the autonomic nervous system carrying information to and from the organs, and the somatic nervous system carrying information to and from the muscles and the external environment. [5]The autonomic nervous system consists of the parasympathetic nervous system that governs resting function and the sympathetic nervous system that governs excitatory functions. The spinal cord and peripheral nerves provide all impulses to control muscle contraction, cardiac rhythm, pain and other bodily functions so therefore any lesion to the spinal cord prevents or reduces transmission of this information to and from the brain to the peripheries, affecting movement, sensation and visceral function. [6]
 
#
These are:
#Central Nervous System (CNS)
#Peripheral Nervous System (PNS)
[[Image:Nervous System.jpg|center|Nervous System]]
[[Image:Nervous System.jpg|center|Nervous System]]
== Anatomy of the Spinal Cord ==
The spinal cord lies within the vertebral canal, extending from the foramen magnum to the lowest border of the first lumbar vertebra. It is enlarged at two sites, the cervical and lumbar region. The lower part of the spinal canal contains the lower lumbar and sacral nerves known as the '''Cauda Equina'''.
* Sensory Nerve Fibres enter the Spinal Cord via the&nbsp;'''Dorsal (Posterior) Root'''. The cell bodies for these neurons are situated in the Dorsal Root Ganglia.


*Motor and Preganglionic Autonomic Fibres exit via the '''Ventral (Anterior) Root.'''


{| width="50%" cellspacing="1" cellpadding="1"
== '''Structure''' ==
|-
| [[Image:Cord.jpg|left|400px]]
| [[Image:Spinalnerves.jpg|left|400px]]
|}


This short video clip gives an overview of spinal cord anatomy.  
=== Spinal Column ===
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The spine or vertebral column bears the weight of the head, neck, trunk and upper extremities. The adult vertebral column typically consists of 33 vertebrae arranged in five regions, which provide support and protection for the spinal cord'''.'''  It consists of seven cervical, twelve thoracic, five lumbar, five sacral and four coccygeal vertebrae, The five sacral vertebrae are fused in adults to form the sacrum, and the four coccygeal vertebrae are fused to form the coccyx. Its uppermost vertebrae incorporating the atlas and axis articulate with the head, and the lower most portion, the sacrum articulates with the pelvis. Each pair of adjacent vertebrae is separated by a semi-rigid intervertebral disk, which provides a level of flexibility to the vertebral column. Its flexibility is greatest in the cervical region, and lowest in the thoracic region. (Colour Atlas of Neurology - Reinhard Rohkamm)


{| width="400" cellspacing="1" cellpadding="1" border="0" align="center"
|-
| {{#ev:youtube|5B87zsAKmWc|350}}<ref>Handwritten tutorials. Spinal Pathways 1 - Spinal Cord Anatomy and Organisation. Available from: http://www.youtube.com/watch?v=5B87zsAKmWc [last accessed 29/08/16] </ref>
|}


== Associated Pathways ==
=== Spinal Canal ===
=== Ascending Sensory Pathway ===
<div align="justify">
==== [[Spinothalamic tract|Spinothalamic Tract]] ====
Formed by the vertebral foramina of the vertebral bodies the spinal canal is bound anteriorly by the vertebral bodies and posteriorly by the laminae (vertebral arches) with reinforcement at the walls through the intervertebral disks and the anterior and posterior longitudinal ligaments. Containing the spinal cord, meninges, blood vessels, spinal nerve roots and surrounding fatty and connective tissues the diameter varies from 12 to 22 mm in the cervical region and from 22 to 25 mm in the lumbar region. (Colour Atlas of Neurology - Reinhard Rohkamm)
* From Dorsal horn laminae I,III,IV,V. crosses midline in spinal cord, projects to brain stem and contr-lateral thalamus. Conveys pain and temperature.


==== Dorsal Column Medial Lemniscal Pathway ====
* Afferents from mechanoreceptors, muscle and joint receptors. terminates in dorsal column nuclei of medulla. Forms medial lemniscus at this level and synapses in ventroposterior nucleus of thalamus. Conveys proprioception, light touch and vibration.


==== Spinocerebellar Tract ====
=== Spinal Cord ===
* From spinal cord interneurons. It has two tracts a) Dorsal SCT relays via inferior cerebellar peduncle and b) VCT relays via superior cerebellar peduncle to the cerebellum. It conveys proprioceptive information and on-going activity in the spinal cord interneurons.
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The spinal cord is the major conduit and reflex centre between the peripheral nerves and the brain, and transmits motor information from the brain to the muscles, tissues and organs, and sensory information from these areas back to the brain. [5][6 ]The spinal cord in an adult is approximately a 45 cm long, cylindrical structure that is slightly flattened anteriorly and posteriorly. (Essential Clinical Anatomy) The spinal cord lies within the vertebral canal, extending from the foramen magnum to the lowest border of the first lumbar vertebra. It is enlarged at two sites, the cervical and lumbar region. Its upper end is continuous with the medulla; the transition is defined to occur just above the level of exit of the first pair of cervical nerves. Its tapering lower end, the conus medullaris, terminates at the level of the L3 vertebra in neonates, and at the level of the L1-2 intervertebral disk in adults. The conus medullaris is continuous at its lower end with the threadlike filum terminale, composed mainly of glial and connective tissue, which, in turn, runs through the lumbar sac amidst the posterior and anterior roots of the spinal nerves, collectively called the cauda equina (“horse’s tail”), and then attaches to the dorsal surface of the coccyx. (Colour Atlas of Neurology - Reinhard Rohkamm)
* Sensory Nerve Fibres enter the Spinal Cord via the&nbsp;Posterior (Dorsal) Root. The cell bodies for these neurons are situated in the Dorsal Root Ganglia.


=== Descending Motor Pathways ===
*Motor and Preganglionic Autonomic Fibres exit via the Anterior (Ventral) Root.


==== [[Corticospinal Tract|Corticospinal (Pyramidal) Tract]] ====
=== Spinal Nerves ===
From the motor cortex, premotor cortex, and somatosensory cortex. Has a role in sensory processing and fractionated finger movements.
<div align="justify">
Emerging from the spinal cord are 31 pairs of anterior and posterior nerve roots. The cervical, thoracic, lumbar, and sacral portions of the spinal cord are defined according to the segmental division of the vertebral column and spinal nerves. There are eight cervical*, twelve thoracic, five lumbar, five sacral and one coccygeal. At each level an anterior pair of nerve roots carries motor nerves, while a posterior pair of nerve roots carries only sensory nerves. The anterior and posterior roots join to form two spinal nerves, one on either side of the spine, which then exit the vertebral canal through the intervertebral foramina. Once outside the intervertebral foramina they form peripheral nerves. (Colour Atlas of Neurology - Reinhard Rohkamm)


==== [[Rubrospinal Tract]] ====
[[File:Spinalnerves.jpg|frameless]]*While there are eight pairs of cervical spinal nerves there are only seven cervical vertebrae. This disparity occurs because the first pair of cervical spinal nerves exits ''above'' the first cervical vertebra just below the skull. However, the eighth pair of cervical spinal nerves exits ''below'' the last cervical vertebra.*
Originates from the magnocellular part of the red nucleus in the brain. It projects towards common structures with the CoST, particularly those involved with distal motor control. There is debate as to how significant this tract is.


==== [[Vestibulospinal Tract|Vestibulospinal Tract]] ====
This short video clip gives an overview of spinal cord anatomy.  
Originates from Deiters nucleus in the medulla and innervates the extensor and axial muscles. It is involved in balance control and posture.


==== [[Reticulospinal Tract|Reticulospinal Tract]] ====
{| width="400" cellspacing="1" cellpadding="1" border="0" align="center"
This tract begins in the caudal reticular formation in the pons and medulla. Provides both excitable and inhibitory effects on the interneurons in the spinal cord, and to a lesser extent, it also acts on the motor neurons. Its main action is to dampen down activity in the spinal cord. without this pathway, there is increased extensor tone observed.
|-
 
| {{#ev:youtube|5B87zsAKmWc|350}}<ref>Handwritten tutorials. Spinal Pathways 1 - Spinal Cord Anatomy and Organisation. Available from: http://www.youtube.com/watch?v=5B87zsAKmWc [last accessed 29/08/16] </ref>
'''Spinal Motorneurons'''
|}
 
Alpha and Gamma motorneurons (MNs) are both found in the ventral (anterior) horn.&nbsp;<br>  
 
''Alpha motorneurons'' are the largest motor neurons in the nervous system. They innervate skeletal muscle.
 
''Gamma Motorneurons'' innervate intrafusal muscle fibres of the muscle spindle.
 
Motor neurons are arranged somatotopically across the ventral horn. The more medially placed MNs innervate proximal muscles while laterally placed MNs innervate distal muscles.
 
== Blood Supply ==
The spinal cord is supplied by a single anterior spinal artery and paired posterior spinal arteries. Anterior spinal artery: arises from the vertebral arteries and extends from the level of the lower brainstem to the tip of the conus medullaris. It supplies the ventral medial surface of the medulla and anterior 2/3 of the spinal cord. The posterior spinal arteries supply the dorsal 1/3 of the cord. There are reinforcing branches from other arteries along the length of the cord. If occlusion occurs, it is normally of the anterior spinal artery, producing loss of power and spinothalamic sensory deficit, but dorsal column sensory capabilities are maintained.
 
== References  ==


== References ==
<references />  
<references />  


[[Category:Spinal Cord Injuries]]  
[[Category:Spinal Cord Injuries]]  
[[Category:SCI Content Project]]
[[Category:SCI Content Project]]

Revision as of 15:35, 2 December 2018

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Introduction[edit | edit source]

The nervous system is divided into the central nervous system (brain and spinal cord considered upper motor neurons) and the peripheral nervous system (nerves that enter and exit the spinal cord considered lower motor neurons).[1] Information to and from the muscles, glands, organs and sensory receptors are carried through the peripheral nervous system, which is divided into the autonomic nervous system carrying information to and from the organs, and the somatic nervous system carrying information to and from the muscles and the external environment. [5]The autonomic nervous system consists of the parasympathetic nervous system that governs resting function and the sympathetic nervous system that governs excitatory functions. The spinal cord and peripheral nerves provide all impulses to control muscle contraction, cardiac rhythm, pain and other bodily functions so therefore any lesion to the spinal cord prevents or reduces transmission of this information to and from the brain to the peripheries, affecting movement, sensation and visceral function. [6]

Nervous System


Structure[edit | edit source]

Spinal Column[edit | edit source]

The spine or vertebral column bears the weight of the head, neck, trunk and upper extremities. The adult vertebral column typically consists of 33 vertebrae arranged in five regions, which provide support and protection for the spinal cord.  It consists of seven cervical, twelve thoracic, five lumbar, five sacral and four coccygeal vertebrae, The five sacral vertebrae are fused in adults to form the sacrum, and the four coccygeal vertebrae are fused to form the coccyx. Its uppermost vertebrae incorporating the atlas and axis articulate with the head, and the lower most portion, the sacrum articulates with the pelvis. Each pair of adjacent vertebrae is separated by a semi-rigid intervertebral disk, which provides a level of flexibility to the vertebral column. Its flexibility is greatest in the cervical region, and lowest in the thoracic region. (Colour Atlas of Neurology - Reinhard Rohkamm)


Spinal Canal[edit | edit source]

Formed by the vertebral foramina of the vertebral bodies the spinal canal is bound anteriorly by the vertebral bodies and posteriorly by the laminae (vertebral arches) with reinforcement at the walls through the intervertebral disks and the anterior and posterior longitudinal ligaments. Containing the spinal cord, meninges, blood vessels, spinal nerve roots and surrounding fatty and connective tissues the diameter varies from 12 to 22 mm in the cervical region and from 22 to 25 mm in the lumbar region. (Colour Atlas of Neurology - Reinhard Rohkamm)


Spinal Cord[edit | edit source]

The spinal cord is the major conduit and reflex centre between the peripheral nerves and the brain, and transmits motor information from the brain to the muscles, tissues and organs, and sensory information from these areas back to the brain. [5][6 ]The spinal cord in an adult is approximately a 45 cm long, cylindrical structure that is slightly flattened anteriorly and posteriorly. (Essential Clinical Anatomy) The spinal cord lies within the vertebral canal, extending from the foramen magnum to the lowest border of the first lumbar vertebra. It is enlarged at two sites, the cervical and lumbar region. Its upper end is continuous with the medulla; the transition is defined to occur just above the level of exit of the first pair of cervical nerves. Its tapering lower end, the conus medullaris, terminates at the level of the L3 vertebra in neonates, and at the level of the L1-2 intervertebral disk in adults. The conus medullaris is continuous at its lower end with the threadlike filum terminale, composed mainly of glial and connective tissue, which, in turn, runs through the lumbar sac amidst the posterior and anterior roots of the spinal nerves, collectively called the cauda equina (“horse’s tail”), and then attaches to the dorsal surface of the coccyx. (Colour Atlas of Neurology - Reinhard Rohkamm)

  • Sensory Nerve Fibres enter the Spinal Cord via the Posterior (Dorsal) Root. The cell bodies for these neurons are situated in the Dorsal Root Ganglia.
  • Motor and Preganglionic Autonomic Fibres exit via the Anterior (Ventral) Root.

Spinal Nerves[edit | edit source]

Emerging from the spinal cord are 31 pairs of anterior and posterior nerve roots. The cervical, thoracic, lumbar, and sacral portions of the spinal cord are defined according to the segmental division of the vertebral column and spinal nerves. There are eight cervical*, twelve thoracic, five lumbar, five sacral and one coccygeal. At each level an anterior pair of nerve roots carries motor nerves, while a posterior pair of nerve roots carries only sensory nerves. The anterior and posterior roots join to form two spinal nerves, one on either side of the spine, which then exit the vertebral canal through the intervertebral foramina. Once outside the intervertebral foramina they form peripheral nerves. (Colour Atlas of Neurology - Reinhard Rohkamm)

Spinalnerves.jpg*While there are eight pairs of cervical spinal nerves there are only seven cervical vertebrae. This disparity occurs because the first pair of cervical spinal nerves exits above the first cervical vertebra just below the skull. However, the eighth pair of cervical spinal nerves exits below the last cervical vertebra.*

This short video clip gives an overview of spinal cord anatomy.

[2]

References[edit | edit source]

  1. Barker; Barasi; Neal. Neuroscience at a glance; Blackwell science Ltd; 1999
  2. Handwritten tutorials. Spinal Pathways 1 - Spinal Cord Anatomy and Organisation. Available from: http://www.youtube.com/watch?v=5B87zsAKmWc [last accessed 29/08/16]