Spondylodiscitis: Difference between revisions

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== Definition/Description  ==
== Definition/Description  ==


Spondylodiscitis can be defined as a primary infection (accompanied by destruction) of the intervertebral disc (discitis), with secondary infections of the vertebrae (spondylitis), starting at the endplates <ref name="1">T. Gouliouris et al., Spondylodiscitis: update on diagnosis and management, Journal of antimicrobial chemotherapy, 2010; 65 Suppl 3: iii11–24. (Level of evidence 2A)</ref><ref name="2">F. Postacchini, 1999, Lumbar disc herniation, Springer, 481p. (Level of evidence 5)</ref><ref name="12">Fransen B.L. et al., Recommendations for diagnosis and treatment of spondylodiscitis, The Netherlands Journal of Medicine 2014. (level of evidence 2B)</ref><ref name="15">Enrique G. et al., Surgical treatment of spondylodiscitis. An update, International Orthopaedics  2012. (level of evidence 5)</ref>. It can lead to osteomyelitis of the spinal column <ref name="3">M. Titlic et al., Spondylodiscitis, Journal Citation/ Science Edition, 2008; 109(8) 345-347. (Level of evidence 2A)</ref><ref name="2" />. It has a high morbidity and mortality and is a rare but serious infection.<ref name="1" /><ref name="12" /><ref name="13">Jensen AG. et al., Bacteremic Staphylococcus aureus spondylitis, Archives of Internal Medicine 1998. (level of evidence 2C)</ref><ref name="15" /><ref name="17">Sans N. et al., Infections of the spinal column — Spondylodiscitis, Diagnostic and Interventional Imaging 2012. (level of evidence 5)</ref>
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Pathogens causing spondylodiscitis are staphylococci, Escheria coli and mycobacterium tuberculosis <ref name="1" /><ref name="2" /><ref name="4">M. Hasenbring et al., Intervertebral disk diseases, Thieme, 2008, 236p. (Level of evidence 5)</ref><ref name="5">A.L. Baert et al., Imaging in percutaneous musculoskeletal interventions, Springer, 2009, 120p. (Level of evidence 5)</ref><ref name="12" /><ref name="14">Gerometta A. et al., Postoperative spondilodiscitis, International Othopaedics  2012. (level of evidence 4)</ref><ref name="16">Kapsalaki E. et al., Spontaneous spondylodiscitis: presentation, risk factors, diagnosis, management, and outcomes, International Journal of Infectious Diseases 2009. (level of evidence 1B)</ref>.Spinal infections can be described aetiologically as pyogenic, granulomatous (tuberculous, brucellar, fungal) and parasitic. Pyogenic spinal infections include: spondylodiscitis, a term encompassing vertebral osteomyelitis, spondylitis and discitis[<ref name="1" /><ref>16</ref>. <br>&nbsp;<br>


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Revision as of 20:35, 25 April 2016

Welcome to Vrije Universiteit Brussel's Evidence-based Practice project. This space was created by and for the students in the Rehabilitation Sciences and Physiotherapy program of the Vrije Universiteit Brussel, Brussels, Belgium. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

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