Mixed Connective Tissue Disease: Difference between revisions
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== Definition/Description == | == Definition/Description == | ||
Mixed connective tissue disease (MCTD) is a systemic disease which consists of clinical symptoms observed in the three following disorders: systemic lupus erythematosus, polymyositis, and systemic sclerosis.<sup>[1,9]</sup> MCTD is considered an overlapping disease due to the features of these three disorders which can be categorized broadly as arthritic changes, cardiopulmonary dysfunctions, skin changes, muscle weakness, kidney disease, and dysfunctions of the esophagus.<sup>[10]</sup> | |||
The symptoms associated with the three underlying disorders do not usually present all at once.4 In fact, it usually takes several years before the symptoms of each individual disorder present which ultimately complicates the diagnosis of MCTD.<sup>[4] </sup>Typically, the hands are affected and present as the first symptom of MCTD. Swelling to the fingers or the presentation of “sausage fingers” is common. As the disease progresses, it can often affect the organs such as lungs, heart or the kidneys. There is no definite cure for MCTD, however side effects can be managed through the use of medications.<sup>[5]</sup><br><br> | |||
== Prevalence == | == Prevalence == |
Revision as of 18:38, 10 April 2016
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Top Contributors - Erica Hunter, Laci Sattler, Bridget Ward, Vidya Acharya, Kim Jackson, Elaine Lonnemann, Sehriban Ozmen and WikiSysop
Definition/Description[edit | edit source]
Mixed connective tissue disease (MCTD) is a systemic disease which consists of clinical symptoms observed in the three following disorders: systemic lupus erythematosus, polymyositis, and systemic sclerosis.[1,9] MCTD is considered an overlapping disease due to the features of these three disorders which can be categorized broadly as arthritic changes, cardiopulmonary dysfunctions, skin changes, muscle weakness, kidney disease, and dysfunctions of the esophagus.[10]
The symptoms associated with the three underlying disorders do not usually present all at once.4 In fact, it usually takes several years before the symptoms of each individual disorder present which ultimately complicates the diagnosis of MCTD.[4] Typically, the hands are affected and present as the first symptom of MCTD. Swelling to the fingers or the presentation of “sausage fingers” is common. As the disease progresses, it can often affect the organs such as lungs, heart or the kidneys. There is no definite cure for MCTD, however side effects can be managed through the use of medications.[5]
Prevalence[edit | edit source]
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