Ramsay Hunt Syndrome: Difference between revisions

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In particular,&nbsp;VZV antigen detection by direct immunofluorescence assay (DFA) is used, which has sensitivity of 90% and specificity close to 99%<ref>Coffin SE, Hodinka RL. Utility of direct immunofluorescence and virus culture for detection of varicella-zoster virus in skin lesions. J Clin Microbiol. 1995 Oct. 33(10):2792-5</ref>.  
In particular,&nbsp;VZV antigen detection by direct immunofluorescence assay (DFA) is used, which has sensitivity of 90% and specificity close to 99%<ref>Coffin SE, Hodinka RL. Utility of direct immunofluorescence and virus culture for detection of varicella-zoster virus in skin lesions. J Clin Microbiol. 1995 Oct. 33(10):2792-5</ref>.  
Structural lesions (such as Acoustic Neuroma) can be ruled out by MRI or&nbsp;CT scan.<br>


== Outcome Measures  ==
== Outcome Measures  ==

Revision as of 23:00, 7 December 2015

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Clinically Relevant Anatomy
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Mechanism of Injury / Pathological Process
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Clinical Presentation[edit | edit source]

The presenting feature is often pain deep within the ear. 

A herpetic rash or blisters, which may be on the skin of the ear canal, auricle or both.

Diagnostic Procedures[edit | edit source]

In most cases, the diagnosis is made purely on clinical findings: the presence of herpetic blisters in and around the ear, accompanied in most cases by pain in and around the ear and an ipsilateral facial palsy.

On occasions virological studies, both serological and molecular, can be used to confirm the clinical diagnosis.

In particular, VZV antigen detection by direct immunofluorescence assay (DFA) is used, which has sensitivity of 90% and specificity close to 99%[1].

Structural lesions (such as Acoustic Neuroma) can be ruled out by MRI or CT scan.

Outcome Measures[edit | edit source]

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Management / Interventions
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Differential Diagnosis
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Resources
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References[edit | edit source]

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  1. Coffin SE, Hodinka RL. Utility of direct immunofluorescence and virus culture for detection of varicella-zoster virus in skin lesions. J Clin Microbiol. 1995 Oct. 33(10):2792-5