Sciatica

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Description

Sciatica is a debilitating condition in which the patient experiences pain and/or paresthesias and/or weakness in the distribution of the sciatic nerve or an associated lumbosacral nerve root.

• A common mistake is referring to any low back pain or radicular leg pain as sciatica.
• Sciatica is a clinical diagnosis based on the presence of radiating pain in one leg, with or without the associated neurological deficits of parasthesia and muscle weakness, which are the direct result of sciatic nerve or sciatic nerve root pathology.
• The sciatic nerve is made up of the L4 through S2 nerve roots which coalesce at the pelvis to form the sciatic nerve. At up to 2 cm in diameter, the sciatic nerve is easily the largest nerve in the body. 
• Sciatica pain often is worsened with flexion of the lumbar spine, twisting, bending, or coughing.
• The sciatic nerve provides direct motor function to the hamstrings, lower extremity adductors, and indirect motor function to the calf muscles, anterior lower leg muscles, and some intrinsic foot muscles.
• Indirectly through its terminal branches, the sciatic nerve provides sensation to the posterior and lateral lower leg as well as the plantar foot.

The following video gives a summary of sciatica.

Video:

Etiology

Any condition that may structurally impact or compress the sciatic nerve may cause sciatica symptoms.

Sciatic nerve injury can also result in sciatica symptoms (such as pain, muscle weakness and parasthesia) and is usually caused by a traumatic injury (pressure, stretching or cutting), rather than compression or irritation of the nerve. Please read our sciatic nerve injury page for more information.

The causes of sciatica can be categorised into spinal or non-spinal causes or iatrogenic:

Spinal causes:

• Spinal stenosis (due to degenerative bone disorders, trauma, inflammatory disease)
• Spondylolisthesis
• Herniated or bulging lumbar intervertebral disc
• Spinal or paraspinal mass (malignancy, epidural hematoma or abscess)

Non Spinal causes:

• Piriformis syndrome
• Pregnancy
• Lumbar Radiculopathy
• Pelvic tumours
• Trauma to leg

Iatrogenic causes:

• Direct surgical trauma
• Faulty positioning during anaesthesia
• Injection of neurotoxic substances
• Tourniquets
• Dressings, casts or faulty fitting orthotics
• Radiation

Epidemiology

• Annual incidence of 1% to 5%
• Lifetime incidence reported between 10% to 40%
• No gender predominance
• Peak incidence occurs in patients in their fourth decade
• Rarely occurs before age 20 (unless traumatic)
• No association with body height has been established except in the age 50 to 60 group
• Increased incidence in those with poor general health (including presence of co-morbidities and smoking) and the presence of psychological factors such as depression
• Physical activity increases incidence in those with prior sciatic symptoms and decreased in those with no prior symptoms.
• Occupational predisposition has been shown in machine operators, truck drivers, and jobs where workers are subject to physically awkward positions or physical stress on the spine such as vibration

Clinical Presentation

Patients with sciatica can present with neurological symptoms such as:

• Radicular pain in the distribution of the lumbosacral nerve root
• Sensory impairment/disturbance, such as hot and cold or tingling/ burning sensations in the legs or numbness
• Muscular weakness
• Reflex impairment
• Gait dysfunction

Sciatica symptoms of paresthesias or dysesthesias and oedema in the lower extremity can differ, depending on which nerve is affected

• L4: When the L4 nerve is compressed or irritated, the patient feels pain, tingling and numbness in the thigh. The patient also feels weak when straightening the leg and may have a diminished knee jerk reflex.
• L5: When the L5 nerve is compressed or irritated, the pain, tingling and numbness may extend to the foot and big toes.
• S1: When the S1 nerve is compressed or irritated, the patient feels pain, tingling and numbness on the outer part of the foot. The patient also experiences weakness when elevating the heel off the ground and standing on tiptoes. The ankle jerk reflex may be diminished.

Differential Diagnosis

A thorough differential list is important in considering a diagnosis of sciatica and should include.

• Herniated lumbosacral disc
• Cauda Equina syndrome
• Muscle spasm
• Nerve root impingement
• Epidural abscess
• Epidural hematoma
• Tumor
• Potts Disease, also known as spinal tuberculosis
• Piriformis syndrome

Evaluation

Sciatica is most commonly diagnosed by:

1. History

• Complaints of radiating pain in the leg, which follows a dermatomal pattern
• Pain generally radiates below the knee, into the foot
• Patients complain about low back pain, which is usually less severe than the leg pain
• Patients may also report sensory symptoms.

2. Imaging may be used if pain persists for more than 12 weeks or the patient develops progressive neurological deficits

• Plain films of the lumbosacral spine may evaluate for fracture or spondylolisthesis
• Noncontrast CT scan may be performed to evaluate fracture if plain films are negative
• In cases where the neurologic deficit is the present or mass effect is suspected, immediate MRI is the standard of care in establishing the cause of the pain and ruling out pressing surgical pathology

Outcome Measures

Many to choose from, below are but a few, all dependant on cause and assessment.

• Short Form-36 bodily pain (SF-36 BP)
• Oswestry disability index
• Roland-Morris disability index
• VAS-score: one of leg pain and one of back pain
• McGill pain Questionnaire: this questionnaire looks at the location, intensity, quality and pattern of the pain as well as alleviating and aggravating factors
• VAS
• TUG
• Tampa Scale for Kinesiophobia
• Pain Catastrophising Scale

Examination

Clinicians should always look for and inquire about red flags when evaluating sciatica or in patients who present with any low back pain. Patients with signs of urinary retention or decreased anal sphincter tone should be urgently referred for investigation as this suggests cauda equina syndrome.

• See Lumbar Assessment

Medical Management

Most patients improve over time with conservative treatment including exercise, manual therapy, and pain management

• Pharmacology: a short course of oral NSAIDs; Opioid and non-opioid analgesics; muscle relaxants; anticonvulsants for neurogenic pain; localized corticosteroid injections.
• Surgical evaluation: to address structural abnormalities such as: disc herniation, epidural hematoma, epidural abscess or tumour may be considered if no improvement following 6-8 weeks of conservative treatment. One study found that although it may speed up recovery, the effect is similar to conservative care at one year
• Physical therapy management (see below)

Physical Therapy Management

In most cases of sciatica, conservative treatment is favoured. The evidence does not show that one treatment is superior to the other

• Patient Education: to include information on the nature of low back back, advice on self-management techniques and encouragement to continue normal activities

• Promote self management techniques such as: use of hot or cold packs for comfort and to decreased inflammation; avoidance of inciting activities or prolonged sitting/standing, Regularly changing position i.e. from sitting to standing, practicing good, erect posture, use of proper lifting techniques
• Exercise: exercises to increase core strength, gentle stretching of the lumbar spine and hamstrings, regular light exercise such as walking, swimming, or aquatherapy
• Manual therapy: spinal manipulation, mobilisation or soft tissue techniques such as massage - used alongside exercise and patient education

For comprehensive treatment see Links below

1. Disc Herniation
2. Lumbar Discogenic Pain
3. Spinal Stenosis
4. Degenerative Disc Disease
5. Spondylolisthesis
6. Piriformis Syndrome
7. Sacroiliac Joint Dysfunction
8. Sciatic Nerve Injury
9. Corticosteroid injections
10. Acupuncture
11. Massage therapy

Concluding Remarks

• 
  The key to sciatica is patient education.
• There are many causes of sciatica and the disorder is best managed with a team of healthcare professionals that includes an orthopedic surgeon, physical therapist, neurologist, rehabilitation nurse, and a pain specialist.
• The majority of cases of sciatica are best managed conservatively.
• Patients should be encouraged by the clinician and nurse to lose weight, stop smoking and enroll in a physical therapy program.
• Bed rest should be limited.
• The pharmacist should caution the patient against the use of prescription-strength medications to avoid dependence and other adverse effects.
• Surgery should only be undertaken when conservative methods have failed.
• Regular exercise is essential